HOME | 研究内容 | 原著論文 2003-4年

56) Induction of cyclooxygenase-2 expression by fluid shear stress in vascular endothelial cells. Inoue H, Taba Y, Miwa Y, Yokota C, Miyagi M, Sasaguri T. Adv Exp Med Biol. 525, 141-144 (2003)

57) Post-ischemic cyclooxygenase-2 expression is regulated by the extent of cerebral blood flow reduction in non-human primates. Yokota C, Kuge Y, Inoue H, Tagaya M, Kito G, Susumu T, Tamaki N, Minematsu K. Neurosci. Lett. 341, 37-40 (2003)

58) 15-Deoxy-12,14-prostaglandin J2 and laminar shear stress stabilize c-IAP1 in vascular endothelial cells. Y. Taba, M. Miyagi M, Y. Miwa, H. Inoue, F. Takahashi-Yanaga, S. Morimoto, T. Sasaguri  Am J Physiol Heart Circ Physiol. 285, H38-H46 (2003)  →  Link

59) Cyclooxygenase-2 expression associated with spreading depression in a primate model. C. Yokota C, H. Inoue, Y. Kuge, T. Abumiya M. Tagaya, Y. Hasegawa, N. Ejima, N. Tamaki, K. Minematsu. J. Cereb. Blood Flow Metab. 23, 395-398 (2003)

60) Tyrosine Phosphorylation of I-kappaB Kinase alpha/beta by Protein Kinase C-Dependent c-Src Activation Is Involved in TNF-alpha-Induced Cyclooxygenase-2 Expression. W.C. Huang, J.J. Chen JJ, H. Inoue, C.C. Chen J. Immunol. 170, 4767-4775 (2003)  →  Link

61) Control of COX-2 gene expression through peroxisome proliferator-activated receptor  in human cervical cancer cells. S. Han, H. Inoue, LC. Flowers, N. Sidell Clin. Cancer Res. 9, 4627-4635 (2003)  → Link

62) Brain protection by resveratrol and fenofibrate against stroke requires peroxisome proliferator-activated receptor  in mice H. Inoue, X. Jiang, T. Katayama, S. Osada, K. Umesono, S. Namura Neurosci. Lett. 352. 203-206 (2003)

63) Transcriptional regulation of cyclooxygenase 2 by bradykinin and interleukin-1beta in human airway smooth muscle cells: involvement of different promoter elements, transcription factors, and histone h4 acetylation. M. Nie, L. Pang, H. Inoue, A.J. Knox Mol Cell Biol. 24, 9233-44 (2003)  → Link

64) Involvement of the 3’-untranslated region of cyclooxygenase-2 gene in its post-transcriptional regulation throught the glucocorticoid receptor. T. Nishimori, H. Inoue, Y. Hirata Life Sciences 74, 2505-2513 (2004)

65) Characterisation of [(123)I]iomazenil distribution in a rat model of focal cerebral ischaemia in relation to histopathological findings. Kaji T, Kuge Y, Yokota C, Tagaya M, Inoue H, Shiga T, Minematsu K, Tamaki N. Eur J Nucl Med Mol Imaging. 31, 74-70 (2004)

66) HDL3 Induces Cyclooxygenase-2 Expression and Prostacyclin Release in Human Endothelial Cells Via a p38 MAPK/CRE-Dependent Pathway: Effects on COX-2/PGI-Synthase Coupling G. D. Norata, E. Callegari, H. Inoue, A. L. Catapano Artherioscler. Thromb. Vasc. Biol. 24, 871-877 (2004)  → Link

67) Norata GD, Pirillo A, Pellegatta F, Inoue H, Catapano AL. Native LDL and oxidized LDL modulate cyclooxygenase-2 expression in HUVECs through a p38-MAPK, NF-kappaB, CRE dependent pathway and affect PGE2 synthesis. Int J Mol Med. 14, 353-359 (2004)

68) Nakatani K, Yamakuni T, Kondo N, Arakawa T, Oosawa K, Shimura S, Inoue H, Ohizumi Y. -Mangostin Inhibits Inhibitor-B Kinase Activity and Decreases Lipopolysaccharide-Induced Cyclooxygenase-2 Gene Expression in C6 Rat Glioma Cells. Mol Pharmacol. 66, 667-674 (2004) 

69) Chen BC, Yu CC, Lei HC, Chang MS, Hsu MJ, Huang CL, Chen MC, Sheu JR, Chen TF, Chen TL, Inoue H, Lin CH Bradykinin B2 receptor mediates NF-kappaB activation and cyclooxygenase-2 expression via the Ras/Raf-1/ERK pathway in human airway epithelial cells.  J Immunol. 173, 5219-5228 (2004)  → Link

70) Chang YJ, Wu MS, Lin JT, Sheu BS, Muta T, Inoue H, Chen CC. Induction of cyclooxygenase-2 overexpression in human gastric epithelial cells by Helicobacter pylori involves TLR2/TLR9 and c-Src-dependent nuclear factor-kappaB activation. Mol Pharmacol. 66, 1465-1477 (2004)  → Link

71) Yokota C, Kaji T, Kuge Y, Inoue H, Tamaki N, Minematsu K. Temporal and topographic profiles of cyclooxygenase-2 expression during 24 h of focal brain ishemia in rats. Neurosci Lett. 357, 219-222 (2004)

72) Yokota C, Kuge Y, Hasegawa Y, Inoue H, Tagaya M, Abumiya T, Kito G, Tamaki N, Minematsu K. Neuronal cyclooxygenase-2 induction associated with spreading depression and focal brain ischemia in primates. International Congress series 1264, 191-196 (2004)